This newly reorganized and increased moment variation of the progressive reference consultant, Atopic Dermatitis, is the single on hand textual content dedicated to discussing all features of this universal affliction. attractive to dermatologists, allergists, kin practitioners, and pediatricians in day-by-day perform, in addition to surgeon scientists, scientific scholars, and experimental investigators, this stand-alone advisor addresses contemporary step forward discoveries in genetics and new milestones in immunological learn in dermatology.
New highlights within the moment Edition:
12 fresh chapters that surround the newest research
the most modern advances, together with regulatory and Th17 cells in atopic dermatitis, cytokines and chemokines, virus infections, autoantigens, particular immunotherapy, the immune process and atopic dermatitis, and neuromediators and the pathophysiology of pruritus
coverage of the newest components of development: pathophysiology, mechanisms and mobile facets, epidemiologic, genetic, and immunologic facets of atopic dermatitis
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Extra info for Atopic Dermatitis (2nd Edition)
The socioeconomic gradient can also be seen on a wider scale, with disease prevalence being generally higher in more affluent countries with a westernized lifestyle and market economy (15,74). A comparison of disease prevalence in northern and eastern Europe (Fig. 1) shows a higher prevalence of atopic dermatitis in industrialized countries such as Scandinavia, compared to the western part of the SPH SPH IHBK030-02 IHBK030-Bieber February 3, 2009 Epidemiology 17:50 Char Count= 21 formerly disadvantaged socialist region, for example, Estonia, Latvia, and Poland, with the lowest frequency in former socialist countries with a lifestyle even more different from that in western Europe, such as Albania.
There is some evidence that people from less developed countries who move to industrialized countries may become more vulnerable than the local population. For example, IgE levels are significantly higher in migrant Turks residing in Sweden than among similar Swedish residents, with levels declining with increasing periods of residence in the country (93). These studies suggest that environmental factors associated with urbanization and development may be important in the etiology of atopic dermatitis in genetically susceptible individuals.
Williams HC, Robertson C, Stewart A, et al. Worldwide variations in the prevalence of symptoms of atopic eczema in the International Study of Asthma and Allergies in Childhood. J Allergy Clin Immunol 1999; 103:125–138. 75. Flohr C, Johansson SGO, Wahlgren CF, et al. How atopic is atopic dermatitis? J Allergy Clin Immunol 2004; 114:150–158. 76. Flohr C, Weiland SK, Weinmayr G, et al. The role of atopic sensitization in flexural eczema: Findings from the International Study of Asthma and Allergies in Childhood Phase Two.